This course will discuss the book of Modeling differential equation in biology by C. H. Taubes. The book is based on a very successful one-semester course taught at Harvard University for life science students. The book covers the basics of ordinary differential equations, partial differential equations, and dynamic system analysis. Each chapter is with accompanying articles from the current biology and earth science research literatures (most from Science and Nature) that illustrate the utility of the mathematics learned in the chapter. These articles are to make convincing example that the mathematics learned is essential and relevant to the scientific research. Even the book has the title in biology; the course is suited for general students in science and engineering. The students will be required to read the supporting articles and to present in the class.